Active Research

Research Projects

CORC conducts investigations across all dsciplines in orthopaedics. Our projects leverage shared data infrastructure and collaborative expertise to generate high-quality information for clinical practice.

SubmittedRetrospective StudySurgical Cancellations

PAT-TJA

Characterizing Preventable Surgical Cancellations Due to Undiagnosed and Uncontrolled Conditions in an Urban Underserved Orthopaedic Population Undergoing Total Joint Arthroplasty

Kathleen Cain, Virginia He, Ira Kirschenbaum, MD

This study analyzes preventable surgical cancellations in an urban underserved orthopaedic population undergoing total joint arthroplasty, examining the role of undiagnosed and uncontrolled medical conditions and evaluating strategies to optimize preoperative preparation and reduce cancellation rates.

Started

2026

Lead Investigator

Kathleen Cain, Virginia He

SubmittedRetrospective StudyOpioids, Total Joint Arthroplasty

Opioids-TJA

Opioid Prescribing Patterns Following Total Joint Arthroplasty at an Urban Safety-Net Hospital

Kathleen Cain, Navin Ramesh, Anant Jhaveri, Rohan Panjwani, Ira Kirschenbaum, MD, Joshua Auerbach, MD

This study examines opioid prescribing patterns following total joint arthroplasty at an urban safety-net hospital, evaluating prescription volumes, patient-level risk factors, and opportunities to optimize postoperative pain management protocols.

Started

2026

Lead Investigator

Kathleen Cain, Navin Ramesh

SubmittedRetrospective StudyPostoperative Complications, Social Determinants of Health

TKA-MUA-SDH

Elevated Manipulation Under Anesthesia Rate After Primary TKA at an Urban Safety-Net Hospital: Risk Factors and Social Determinants

Anant Jhaveri, Rohan Panjwani, Kathleen Cain, Navin Ramesh, Ira Kirschenbaum, MD

This study aimed to determine the incidence and risk factors for manipulation under anesthesia following primary total knee arthroplasty at an urban safety-net hospital, with emphasis on social determinants of health and physical therapy engagement.

Started

2026

Lead Investigator

Anant Jhaveri

SubmittedRetrospective StudyPostoperative Complications, Physical Therapy

TKA-MUA

Elevated Incidence of Manipulation Under Anesthesia After Primary Total Knee Arthroplasty at an Urban Safety-Net Hospital: Association With Physical Therapy Nonengagement

Rohan Panjwani, Kathleen Cain, Navin Ramesh, Maria Gonzalez, Virginia He, Ira Kirschenbaum, MD

This study evaluated manipulation under anesthesia incidence, clinical and social risk factors, and range-of-motion recovery following manipulation under anesthesia, with particular attention to physical therapy engagement and neighborhood deprivation.

Started

2026

Lead Investigator

Rohan Panjwani

ActiveRetrospective StudySurgical Cancellations, Healthcare Economics

PAT-CANCEL

Pilot Study: Preventable Surgical Cancellations in an Urban Underserved Orthopaedic Population: The Role of Modifiable Factors

Virginia He, Kathleen Cain, Juliette Slyyar, Daniel Asabere, Ira Kirschenbaum, MD

The aim of this study is to analyze whether changing the way we optimize patients preoperatively would prevent cancellations and facilitate earlier intervention of treatment.

Started

2026

Lead Investigator

Kathleen Cain. Virginia He

SubmittedRetrospective StudyComorbidities, PJI

PJI-COMORBIDITY

Characterizing Comorbidity Patterns Among Postoperative Infections After Total Joint Replacement to Identify Perioperative Risk Factors

Alexander Fontecchio, Shayla Hillis, Catherine Esteves, Victoria Zaang, Angela Morcos, Ira Kirschenbaum, MD

This study characterizes comorbidity patterns among patients who develop postoperative infections following total joint replacement to identify perioperative risk factors.

Started

2026

Lead Investigator

Alexander Fontecchio

SubmittedRetrospective StudyHealth Economics

SNF-TJA

Increased SNF and Inpatient Stays at Safety-Net Hospitals: Financial Burdens Post-Joint Procedures

Maria Gonzalez, Kierstin Gehres, Aimee Perales, Gurleen Toor, Carlos Calderon, Ira Kirschenbaum, MD

This study evaluates whether SNF discharge rates and pre-discharge inpatient stays at a safety-net hospital exceed national benchmarks.

Started

2026

Lead Investigator

Maria Gonzalez

SubmittedRetrospective StudyJoint Reconstruction

BMI-TJA

Reevaluating BMI as a Surgical Criterion: Reoperation Rates, Operative Time, and Infection Rates Following Total Joint Arthroplasty

Tina Siu, Carlos Andrés Calderón Rodas, Amelia Wieland, Claudia Sánchez Sayago, Navin Ramesh, Anant Jhaveri, Kathleen Cain, Ira Kirschenbaum, M.D.

A study examining the relationship between body mass index and postoperative outcomes in patients undergoing total joint arthroplasty, including complication rates, length of stay, and functional recovery.

Started

2026

Lead Investigator

Tina Siu

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